Immunological Sciences

PMEL17 / GP100 (2Z15) Rabbit Monoclonal Antibody

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Catalog Number:MABN16301
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Melanoma gp100
Reactivity:Human,Mouse
Applications:WB 1:1000-1:5000,IHC 1:100-1:500,ICC/IF 1:20-1:50,FC 1:200-1:500,IP 1:20-1:50
Molecular Weight:70kDa
Purification:Affinity purification
Form:Liquid
Synonyms:PMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV;

Applications

WB 1:1000-1:5000,IHC 1:100-1:500,ICC/IF 1:20-1:50,FC 1:200-1:500,IP 1:20-1:50

Immunogen

A synthetic peptide of human Melanoma gp100

Target Background

Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.

Synonyms:PMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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