Immunological Sciences

POT1 Rabbit Monoclonal antibody

No images available

Catalog Number:MABN02460
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human POT1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 71 kDa; Observed MW: 71 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide of human POT1

Target Background

This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

Synonyms:POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

No documents available.