POU5F1 Mouse Monoclonal Antibody

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Catalog Number:MABN82902
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human POU5F1 (AA: 136-360) expressed in E. Coli.
Reactivity:Human
Applications:ICC 1:50-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:38.5kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4

Applications

ICC 1:50-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human POU5F1 (AA: 136-360) expressed in E. Coli.

Target Background

This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Synonyms:OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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