Immunological Sciences

PPAR delta (4F4) Mouse Monoclonal Antibody

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Catalog Number:MABN00784
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG1
Clone:Monoclonal
Immunogen:A synthetic peptide of human PPAR delta
Reactivity:Human,Rat,Mouse
Applications:IHC 1:50-1:100
Purification:Affinity Purification
Form:Liquid
Synonyms:FAAR; NR1C2; NUC1; Peroxisome proliferative activated receptor delta

Applications

IHC 1:50-1:100

Immunogen

A synthetic peptide of human PPAR delta

Target Background

Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.

Synonyms:FAAR; NR1C2; NUC1; Peroxisome proliferative activated receptor delta

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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