PRKN Mouse Monoclonal Antibody
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
| Catalog Number: | MABN82302 |
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG2a |
| Clone: | Monoclonal |
| Immunogen: | Purified recombinant fragment of human PRKN (AA: 1-144) expressed in E. Coli. |
| Reactivity: | Human |
| Applications: | ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Molecular Weight: | 6kDa |
| Purification: | Affinity purification |
| Form: | liquid |
| Synonyms: | PDJ; AR-JP; LPRS2; PARK2 |
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
Applications
ELISA 1:5000-1:20000,FC 1:200-1:400
Immunogen
Purified recombinant fragment of human PRKN (AA: 1-144) expressed in E. Coli.
