Immunological Sciences

Proteasome 20S alpha 5/PSMA5 Rabbit Monoclonal Antibody

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Catalog Number:MABN87371
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Proteasome 20S alpha 5/PSMA5
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:100-1:200
Molecular Weight:Calculated MW:26 kDa; Observed MW:26 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PSC5; ZETA

Applications

WB 1:1000-1:5000,IHC 1:100-1:200

Immunogen

A synthetic peptide of human Proteasome 20S alpha 5/PSMA5

Target Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

Synonyms:PSC5; ZETA

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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