Immunological Sciences

PROX1 (11X14) Rabbit Monoclonal Antibody

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Catalog Number:MABN16536
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human PROX1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:200-1:500
Molecular Weight:83kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Homeobox prospero like protein; Prospero homeobox protein 1; prospero-related homeobox gene 1; PROX1;

Applications

WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:200-1:500

Immunogen

Recombinant protein of human PROX1

Target Background

Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.

Synonyms:Homeobox prospero like protein; Prospero homeobox protein 1; prospero-related homeobox gene 1; PROX1;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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