PRPF8 Rabbit Monoclonal Antibody

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Catalog Number:MABN86889
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PRPF8
Reactivity:Human,Mouse,Rat
Applications:WB 1:2000-1:20000,IHC 1:200-1:2000,ICC/IF 1:100-1:200,FC 1:50-1:200
Molecular Weight:Calculated MW:274 kDa; Observed MW:274 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PRP8; RP13; HPRP8; PRPC8; SNRNP220

Applications

WB 1:2000-1:20000,IHC 1:200-1:2000,ICC/IF 1:100-1:200,FC 1:50-1:200

Immunogen

A synthetic peptide of human PRPF8

Target Background

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]

Synonyms:PRP8; RP13; HPRP8; PRPC8; SNRNP220

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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