PSA/KLK3 (9M11) Rabbit Monoclonal Antibody

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Catalog Number:MABN16576
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Prostate Specific Antigen
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,IF-P 1:200-1:1000
Molecular Weight:29kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase; KLK3; APS;

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,IF-P 1:200-1:1000

Immunogen

A synthetic peptide of human Prostate Specific Antigen

Target Background

PSA/KLK3 is a member of the glandular kallikrein subfamily of serine proteases. Upon cleavage of 7 amino-terminal amino acids, it is activated to liquefy semen in the seminal coagulum. Although PSA/KLK3 is produced in healthy individuals, investigators have found abnormally high levels in the blood of men with advanced prostate cancer. Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

Synonyms:Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase; KLK3; APS;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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