PSIP1/LEDGF Rabbit Monoclonal Antibody

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Catalog Number:MABN83756
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human PSIP1
Reactivity:Human
Applications:WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200
Molecular Weight:Calculated MW: 60 kDa ; Observed MW: 75 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:DFS70; LEDGF; p52; p75; PAIP; Psip1; PSIP2;;PSIP1

Applications

WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200

Immunogen

A synthesized peptide derived from human PSIP1

Target Background

Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.

Synonyms:DFS70; LEDGF; p52; p75; PAIP; Psip1; PSIP2;;PSIP1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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