PSMA Rabbit Monoclonal Antibody

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Catalog Number:MABN02489
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PSMA
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 84 kDa; Observed MW: 100 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:FGCP; FOLH 1; GCP 2; GCPII; mGCP; NAALADase I; PSM; PSMA

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide of human PSMA

Target Background

PSMA has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

Synonyms:FGCP; FOLH 1; GCP 2; GCPII; mGCP; NAALADase I; PSM; PSMA

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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