Immunological Sciences

PU.1/Spi1 Rabbit Monoclonal Antibody

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Catalog Number:MABN87221
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PU.1/Spi1
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:500-1:2000
Molecular Weight:Calculated MW:31 kDa; Observed MW:42 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:OF; PU.1; SFPI1; SPI-1; SPI-A

Applications

WB 1:500-1:2000,IHC 1:500-1:2000

Immunogen

A synthetic peptide of human PU.1/Spi1

Target Background

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms:OF; PU.1; SFPI1; SPI-1; SPI-A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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