Immunological Sciences

PURB Mouse Monoclonal Antibody

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Catalog Number:MABN86120
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:This PURB antibody is generated from a mouse immunized with a recombiant protein of human PURB.
Reactivity:Human, Mouse
Applications:WB 1:2000-1:8000
Molecular Weight:33.2kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB

Applications

WB 1:2000-1:8000

Immunogen

This PURB antibody is generated from a mouse immunized with a recombiant protein of human PURB.

Target Background

Has capacity to bind repeated elements in single- stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine- rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity).

Synonyms:Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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