RAB14 Mouse Monoclonal Antibody

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Catalog Number:MABN86078
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:This RAB14 antibody is generated from a mouse immunized with a recombinant protein of human RAB14.
Reactivity:Human, Mouse, Rat
Applications:WB 1:1000-1:2000
Molecular Weight:23.9kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Ras-related protein Rab-14, RAB14

Applications

WB 1:1000-1:2000

Immunogen

This RAB14 antibody is generated from a mouse immunized with a recombinant protein of human RAB14.

Target Background

Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 shedding and cell-cell adhesion.

Synonyms:Ras-related protein Rab-14, RAB14

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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