Rab22A Rabbit Monoclonal antibody

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Catalog Number:MABN02505
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human RAB22A
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 22 kDa; Observed MW: 22 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:Ras-related protein Rab-22A

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

A synthetic peptide of human RAB22A

Target Background

Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes (PubMed:16537905). Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth (PubMed:21849477). Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form (PubMed:16537905).

Synonyms:Ras-related protein Rab-22A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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