Rac3 Rabbit Monoclonal antibody

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Catalog Number:MABN02511
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human RAC3
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100
Molecular Weight:Calculated MW: 21 kDa; Observed MW: 21 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:ras-related C3 botulinum toxin substrate 3 (rho family; small GTP binding protein Rac3)

Applications

WB 1:500-1:1000,IHC 1:50-1:100

Immunogen

A synthetic peptide of human RAC3

Target Background

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.

Synonyms:ras-related C3 botulinum toxin substrate 3 (rho family; small GTP binding protein Rac3)

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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