Immunological Sciences

Rad23A Rabbit Polyclonal Antibody

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Catalog Number:ABN16835
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human RAD23A. AA range:91-140
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,IHC 1:50-1:300
Molecular Weight:48kDa
Purification:Affinity purification
Form:Liquid
Synonyms:RAD23A; UV excision repair protein RAD23 homolog A; HR23A; hHR23A

Applications

WB 1:500-1:2000,IHC 1:50-1:300

Immunogen

The antiserum was produced against synthesized peptide derived from human RAD23A. AA range:91-140

Target Background

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair. Proteins in this family have a modular domain structure consisting of an ubiquitin-like domain (UbL), ubiquitin-associated domain 1 (UbA1), XPC-binding domain and UbA2. The protein encoded by this gene plays an important role in nucleotide excision repair and also in delivery of polyubiquitinated proteins to the proteasome. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012],domain:The ubiquitin-like domain mediates interaction with MJD.,function:Involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA .,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the RAD23 family.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Interacts with MJD. Interacts with HIV-1 Vpr.,

Synonyms:RAD23A; UV excision repair protein RAD23 homolog A; HR23A; hHR23A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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