Immunological Sciences

Rad51 Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN21428
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human Rad51
Reactivity:Human,Mouse,Rat,
Applications:WB 1:1000-1:5000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:37kD;Observed MW:37kD
Purification:Protein A
Form:Liquid
Synonyms:RAD51;RAD51A;RECA;DNA repair protein RAD51 homolog 1;HsRAD51;hRAD51;RAD51 homolog A

Applications

WB 1:1000-1:5000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic peptide of human Rad51

Target Background

Cell localization:Cytoplasm, Nucleus.The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009],

Synonyms:RAD51;RAD51A;RECA;DNA repair protein RAD51 homolog 1;HsRAD51;hRAD51;RAD51 homolog A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

No documents available.