Immunological Sciences

RAIDD Rabbit Monoclonal Antibody

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Catalog Number:MABN02517
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human RAIDD
Reactivity:Human
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 23 kDa; Observed MW: 23 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CRADD; MGC9163; RAIDD; Death adaptor molecule RAIDD; Death domain containing protein CRADD

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

A synthetic peptide of human RAIDD

Target Background

The receptor interacting protein RIP is a death domain-containing serine/threonine kinase which associates with FAS or the TNF-R1 binding protein TRADD. RAIDD (RIP-associated ICH-1/Ced-3 homologous protein with a death domain) has been identified as a RIP binding protein that also associates with members of the caspase family, providing a link between activation of the TNF-Rs and the triggering of the cysteine protease cascade. The amino-terminal domain of RAIDD shares significant homology with the prodomain of ICH-1 and mediates the binding of RAIDD to this cysteine protease.

Synonyms:CRADD; MGC9163; RAIDD; Death adaptor molecule RAIDD; Death domain containing protein CRADD

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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