Immunological Sciences

Ran BP-17 Rabbit Polyclonal Antibody

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Catalog Number:ABN16878
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human RANBP17. AA range:145-194
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,IHC 1:50-1:300
Molecular Weight:125kDa
Purification:Affinity purification
Form:Liquid
Synonyms:RANBP17; Ran-binding protein 17

Applications

WB 1:500-1:2000,IHC 1:50-1:300

Immunogen

The antiserum was produced against synthesized peptide derived from human RANBP17. AA range:145-194

Target Background

RAN binding protein 17(RANBP17) Homo sapiens The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002],function:May function as a nuclear transport receptor.,similarity:Belongs to the exportin family.,subunit:Binds to nucleoporins and the GTP-bound form of Ran.,tissue specificity:Highly expressed in testis, moderately in pancreas and weakly in other tissues studied.,

Synonyms:RANBP17; Ran-binding protein 17

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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