RAP1 Rabbit Monoclonal Antibody

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Catalog Number:MABN02521
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human RAP1A/B
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 21 kDa; Observed MW: 21 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Ras-related protein Rap-1b; K-REV; RAL1B

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

A synthetic peptide of human RAP1A/B

Target Background

GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function.

Synonyms:Ras-related protein Rap-1b; K-REV; RAL1B

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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