RAS Rabbit Monoclonal Antibody

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Catalog Number:MABN87795
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human RAS
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:500-1:2000,ICC/IF 1:50-1:100,FC 1:20-1:50,IP 1:10-1:100
Molecular Weight:Calculated MW:22 kDa; Observed MW:22 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1

Applications

WB 1:1000-1:5000,IHC 1:500-1:2000,ICC/IF 1:50-1:100,FC 1:20-1:50,IP 1:10-1:100

Immunogen

A synthetic peptide of human RAS

Target Background

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]

Synonyms:NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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