Immunological Sciences

RASSF1 Rabbit Monoclonal Antibody

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Catalog Number:MABN87125
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human RASSF1
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:50-1:100
Molecular Weight:Calculated MW:39 kDa; Observed MW:39 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:123F2; RDA32; NORE2A; RASSF1A; REH3P21

Applications

WB 1:1000-1:5000,IHC 1:50-1:100

Immunogen

A synthetic peptide of human RASSF1

Target Background

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]

Synonyms:123F2; RDA32; NORE2A; RASSF1A; REH3P21

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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