Immunological Sciences

RASSF2 Rabbit Polyclonal Antibody

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Catalog Number:ABN16922
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human RASSF2. AA range:109-158
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:50-1:300
Molecular Weight:36kDa
Purification:Affinity purification
Form:Liquid
Synonyms:RASSF2; KIAA0168; Ras association domain-containing protein 2

Applications

WB 1:500-1:2000,IHC 1:50-1:300

Immunogen

The antiserum was produced against synthesized peptide derived from human RASSF2. AA range:109-158

Target Background

This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported. [provided by RefSeq, Jul 2008],function:Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain.,subunit:Interacts directly with activated KRAS in a GTP-dependent manner.,tissue specificity:Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.,

Synonyms:RASSF2; KIAA0168; Ras association domain-containing protein 2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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