Immunological Sciences

RASSF4 Rabbit Polyclonal Antibody

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Catalog Number:ABN16923
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human RASSF4. AA range:134-183
Reactivity:Human,Rat
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight:37kDa
Purification:Affinity purification
Form:Liquid
Synonyms:RASSF4; AD037; Ras association domain-containing protein 4

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human RASSF4. AA range:134-183

Target Background

The function of this gene has not yet been determined but may involve a role in tumor suppression. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described. [provided by RefSeq, Jul 2008],function:Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain.,subunit:Interacts directly with activated KRAS in a GTP-dependent manner.,tissue specificity:Widely expressed. Frequently down-regulated in tumor cell lines.,

Synonyms:RASSF4; AD037; Ras association domain-containing protein 4

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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