RBAK Rabbit Polyclonal Antibody

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Catalog Number:ABN16942
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human RBAK. AA range:1-50
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:2000-1:20000
Molecular Weight:85kDa
Purification:Affinity purification
Form:Liquid
Synonyms:RBAK; ZNF769; RB-associated KRAB zinc finger protein; RB-associated KRAB repressor; hRBaK; Zinc finger protein 769

Applications

WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:50-1:200,ELISA 1:2000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human RBAK. AA range:1-50

Target Background

This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011],function:May repress E2F-dependent transcription. May promote AR-dependent transcription.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 16 C2H2-type zinc fingers.,subunit:Interacts with AR and RB1. May also interact with other nuclear hormone receptors such as NR3C1/GR.,tissue specificity:Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.,

Synonyms:RBAK; ZNF769; RB-associated KRAB zinc finger protein; RB-associated KRAB repressor; hRBaK; Zinc finger protein 769

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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