Recombinant IκB-α Monoclonal Antibody
Western Blot with Recombinant IκB-α Monoclonal Antibody at dilution of 1:1000 dilution. Lane A: Jurkat cell lysate.
| Catalog Number: | MAB300686 |
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Concentration: | 1 mg/mL |
| Host: | Rabbit |
| Isotype: | IgG,κ |
| Clone: | L35A5 |
| Immunogen: | Recombinant Human IκB-α protein |
| Reactivity: | Human;Mouse;Rat |
| Applications: | WB 1:2000-1:10000 |
| Molecular Weight: | 36 kDa |
| Purification: | Protein A |
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Applications
WB 1:2000-1:10000
Immunogen
Recombinant Human IκB-α protein