Immunological Sciences

RET Mouse Monoclonal Antibody

No images available

Catalog Number:MABN85912
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgM
Clone:Monoclonal
Immunogen:This RET Monoclonal antibody was raised using purified His-tagged recombinant human RET.
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:100-1:500,ICC 1:20-1:50
Molecular Weight:124.3kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120 kDa fragment, RET, CDHF12, CDHR16, PTC, RET51

Applications

WB 1:500-1:2000,IHC 1:100-1:500,ICC 1:20-1:50

Immunogen

This RET Monoclonal antibody was raised using purified His-tagged recombinant human RET.

Target Background

This gene, a member of the cadherin superfamily, encodesone of the receptor tyrosine kinases, which are cell-surfacemolecules that transduce signals for cell growth anddifferentiation. This gene plays a crucial role in neural crestdevelopment, and it can undergo oncogenic activation in vivo and invitro by cytogenetic rearrangement. Mutations in this gene areassociated with the disorders multiple endocrine neoplasia, typeIIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease,and medullary thyroid carcinoma. Two transcript variants encodingdifferent isoforms have been found for this gene. Additionaltranscript variants have been described but their biologicalvalidity has not been confirmed.

Synonyms:Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120 kDa fragment, RET, CDHF12, CDHR16, PTC, RET51

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

No documents available.