Immunological Sciences

RGS6 (3A18) Rabbit Monoclonal Antibody

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Catalog Number:MABN17100
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human RGS6
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000
Molecular Weight:54kDa
Purification:Affinity purification
Form:Liquid
Synonyms:GAP; RGS6; S914;

Applications

WB 1:1000-1:5000

Immunogen

A synthetic peptide of human RGS6

Target Background

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/Gbeta5 dimer. Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP- bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509).

Synonyms:GAP; RGS6; S914;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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