Immunological Sciences

RhoA/B/C Rabbit Polyclonal Antibody

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Catalog Number:ABN01372
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Reactivity:Human
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,FC 1:50-1:100
Molecular Weight:Calculated MW: 22 kDa; Observed MW: 22 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ARH12; ARH6; ARH9; ARHA; ARHA2; H12; RHO12; Transforming protein RhoA; RHOA; RHOB; RHOC

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,FC 1:50-1:100

Target Background

RhoA,RhoB,RhoC is a small G protein of the Rho family. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. The three mammalian Rho proteins (A, B and C) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.

Synonyms:ARH12; ARH6; ARH9; ARHA; ARHA2; H12; RHO12; Transforming protein RhoA; RHOA; RHOB; RHOC

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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