RNaseL Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN84271
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human RNase L
Reactivity:Human
Applications:WB 1:1000-1:2000
Molecular Weight:Calculated MW: 84 kDa ; Observed MW: 80 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PRCA1; Ribonuclease4; RibonucleaseL; RNase L; Rnasel; RNS4;;RNase L

Applications

WB 1:1000-1:2000

Immunogen

A synthesized peptide derived from human RNase L

Target Background

Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes.

Synonyms:PRCA1; Ribonuclease4; RibonucleaseL; RNase L; Rnasel; RNS4;;RNase L

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

No documents available.