Immunological Sciences

RNF14 Rabbit Monoclonal Antibody

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Catalog Number:MABN86475
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human RNF14
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,FC 1:10-1:100
Molecular Weight:Calculated MW:54 kDa; Observed MW:54 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ARA54; HFB30; TRIAD2; HRIHFB2038

Applications

WB 1:1000-1:5000,FC 1:10-1:100

Immunogen

A synthetic peptide of human RNF14

Target Background

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]

Synonyms:ARA54; HFB30; TRIAD2; HRIHFB2038

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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