RNF40 Rabbit Monoclonal Antibody

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Catalog Number:MABN84535
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human RNF40
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,IHC 1:100-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW: 114 kDa ; Observed MW: 130 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:BRE 1B; BRE1 B; BRE1B; RBP95; Rnf40; STARING;;RNF40

Applications

WB 1:1000-1:2000,IHC 1:100-1:200,IP 1:20-1:50

Immunogen

A synthesized peptide derived from human RNF40

Target Background

Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively).

Synonyms:BRE 1B; BRE1 B; BRE1B; RBP95; Rnf40; STARING;;RNF40

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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