ROCK1 Rabbit Monoclonal Antibody
Western blot analysis of ROCK1 in K562, C6 lysates using ROCK1 antibody.
| Catalog Number: | AMRe02547 |
| Immunological Catalog: | MABN02547 |
| Conjugate: | Unconjugated |
| Size: | 100 ug |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human ROCK1 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:5000;IHC 1:200-1:1000;IF 1:200-1:1000;IP 1:50-1:200;ELISA 1:5000-1:20000 |
| Molecular Weight: | Observed MW: 158 kDa |
| Purification: | Affinity Purification |
| Form: | Liquid |
| Synonyms: | ROCK1; Rho-associated protein kinase 1; Renal carcinoma antigen NY-REN-35; Rho-associated; coiled-coil-containing protein kinase 1; Rho-associated; coiled-coil-containing protein kinase I; ROCK-I; p160 ROCK-1; p160ROCK |
ROCK1 Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing.
Applications
WB 1:1000-1:5000;IHC 1:200-1:1000;IF 1:200-1:1000;IP 1:50-1:200;ELISA 1:5000-1:20000
Immunogen
A synthetic peptide of human ROCK1