Immunological Sciences

RON Rabbit Monoclonal Antibody

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Catalog Number:MABN86840
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human RON
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:2000
Molecular Weight:Calculated MW:152 kDa; Observed MW:145-150, 100-105 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:RON; PTK8; CD136; NPCA3; CDw136

Applications

WB 1:500-1:2000,IHC 1:200-1:2000

Immunogen

Recombinant protein of human RON

Target Background

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]

Synonyms:RON; PTK8; CD136; NPCA3; CDw136

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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