Immunological Sciences

ROR gamma Rabbit Monoclonal Antibody

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Catalog Number:MABN86763
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse ROR gamma
Reactivity:Mouse
Applications:WB 1:500-1:2000,IHC 1:500-1:2000,FC 1:50-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW:58 kDa; Observed MW:58 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:TOR; Thor; Nr1f3; RORgamma

Applications

WB 1:500-1:2000,IHC 1:500-1:2000,FC 1:50-1:100,IP 1:20-1:50

Immunogen

Recombinant protein of mouse ROR gamma

Target Background

Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respectively.

Synonyms:TOR; Thor; Nr1f3; RORgamma

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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