RPA-70 Monoclonal Antibody

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Catalog Number:MAB-94700
Conjugate:Unconjugated
Size:100ug
Concentration:1mg/ml
Host:Rb
Isotype:IgG
Clone:EPR3472
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RPA70/RPA1 (P27694).
Reactivity:Hu, Rt
Applications:WB 1:500 - 1:2000; IP 1:50 - 1:200
Molecular Weight:70kDa
Purification:Aff. Pr
Form:Liquid
Synonyms:HSSB; MST075; REPA1; RF-A; RP-A; RPA70

Applications

WB 1:500 - 1:2000; IP 1:50 - 1:200

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RPA70/RPA1 (P27694).

Target Background

As part of the heterotrimeric replication protein A complex (RPA/RP-A, binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation.

Synonyms:HSSB; MST075; REPA1; RF-A; RP-A; RPA70

Storage

Store at -20℃.

Buffer

PBS with 0.01% thiomersal, 0.05% BSA, 50% glycerol, pH7.3.

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