Immunological Sciences

RUNX1 Mouse Monoclonal Antibody

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Catalog Number:MABN80972
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Synthesized peptide of human RUNX1.
Reactivity:Human
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight:55kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1; RUNX1

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000

Immunogen

Synthesized peptide of human RUNX1.

Target Background

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.

Synonyms:AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1; RUNX1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

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