RUNX3 Mouse Monoclonal Antibody

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Catalog Number:MABN81173
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG2b
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. Coli.
Reactivity:Human,Mouse
Applications:IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:44.4kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070

Applications

IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. Coli.

Target Background

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms:AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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