RUNX3 Rabbit Monoclonal Antibody

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Catalog Number:MABN87005
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human RUNX3
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:200,FC 1:200-1:500,IP 1:20-1:50
Molecular Weight:Calculated MW:44,46 kDa; Observed MW:44,46 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:AML2; CBFA3; PEBP2aC

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:200,FC 1:200-1:500,IP 1:20-1:50

Immunogen

A synthetic peptide of human RUNX3

Target Background

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Synonyms:AML2; CBFA3; PEBP2aC

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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