Immunological Sciences

RYK Mouse Monoclonal Antibody

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Catalog Number:MABN86036
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:This RYK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 260-565 amino acids from human RYK.
Reactivity:Human, Mouse
Applications:WB 1:500-1:2000,FC 1:25-1:50
Molecular Weight:67.8kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Tyrosine-protein kinase RYK, 2.7.10.1, RYK, JTK5A

Applications

WB 1:500-1:2000,FC 1:25-1:50

Immunogen

This RYK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 260-565 amino acids from human RYK.

Target Background

May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

Synonyms:Tyrosine-protein kinase RYK, 2.7.10.1, RYK, JTK5A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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