Immunological Sciences

S-100 beta

Western Blot (WB) analysis using S-100 beta Monoclonal Antibody against full-length S-100 beta recombinant protein.

Western Blot (WB) analysis using S-100 beta Monoclonal Antibody against full-length S-100 beta recombinant protein.

Catalog Number:MAB-94448
Conjugate:Unconjugated
Size:100 ug
Concentration:1mg/ml
Host:Ms
Isotype:IgG1
Clone:9A11B9
Immunogen:Purified recombinant fragment of S-100 beta expressed in E. Coli.
Reactivity:Hu
Applications:Western Blot: 1:500-1:2000 Immunohistochemistry: 1:200-1:1000 ELISA: 1:10000
Purification:Aff. Pur.
Form:Liquid
Synonyms:Protein S100-B S-100 protein beta chain S-100 protein subunit beta S100 calcium-binding protein B

Applications

Western Blot: 1:500-1:2000 Immunohistochemistry: 1:200-1:1000 ELISA: 1:10000

Immunogen

Purified recombinant fragment of S-100 beta expressed in E. Coli.

Target Background

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Synonyms:Protein S100-B S-100 protein beta chain S-100 protein subunit beta S100 calcium-binding protein B

Storage

Store at -20°C, and avoid repeat freeze-thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide

Western Blot (WB) analysis using S-100 beta Monoclonal Antibody against full-length S-100 beta recombinant protein.

Immunohistochemistry (IHC) analysis of paraffin-embedded Human Brain, cerebellun with DAB staining using S-100 beta Monoclonal Antibody.

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