Immunological Sciences

S100 alpha 6 (12M1) Rabbit Monoclonal Antibody

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Catalog Number:MABN17461
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human S100 alpha 6/PRA
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:50-1:100,ICC/IF 1:200-1:500
Molecular Weight:10kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Protein S100-A6; Calcyclin; MLN 4; PRA; CACY; CABP; 5B10;

Applications

WB 1:500-1:2000,IHC 1:50-1:100,ICC/IF 1:200-1:500

Immunogen

Recombinant protein of human S100 alpha 6/PRA

Target Background

S100A6 (calcyclin) is involved in a number of cellular processes, including exocytosis and cell cycle regulation. In addition, S100A6 interacts with a number of proteins such as SIP, GAPDH, and annexins in a calcium-dependent fashion. Research studies demonstrate that a down regulation of corresponding S100A6 gene expression causes a decrease in cell proliferation. May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.

Synonyms:Protein S100-A6; Calcyclin; MLN 4; PRA; CACY; CABP; 5B10;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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