Immunological Sciences

S100P (5R5) Rabbit Monoclonal Antibody

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Catalog Number:MABN17476
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human S100P
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:200-1:2000,ICC/IF 1:200-1:500,FC 1:200-1:1000,IP 1:20-1:50
Molecular Weight:10kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Protein S100-E; Protein S100P; S100 calcium binding protein P; S100E;

Applications

WB 1:1000-1:5000,IHC 1:200-1:2000,ICC/IF 1:200-1:500,FC 1:200-1:1000,IP 1:20-1:50

Immunogen

A synthetic peptide of human S100P

Target Background

S100 proteins regulate a variety of cellular processes such as cell growth and motility, cell cycle progression, transcription, and differentiation. S100P, a member of the S100 family, is a 95 amino acid protein. Its expression is increased in a number of tumors including pancreas, lung, breast, and ovary carcinomas in response to transcriptional activation. May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).

Synonyms:Protein S100-E; Protein S100P; S100 calcium binding protein P; S100E;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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