SAE1 Rabbit Monoclonal Antibody

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Catalog Number:MABN02568
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human SAE1
Reactivity:Human
Applications:WB 1:500-1:1000,ICC/IF 1:50-1:200
Molecular Weight:Calculated MW: 38 kDa; Observed MW: 38 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:SAE1; AOS1; SUA1; UBLE1A; SUMO-activating enzyme subunit 1; Ubiquitin-like 1-activating enzyme E1A

Applications

WB 1:500-1:1000,ICC/IF 1:50-1:200

Immunogen

A synthetic peptide of human SAE1

Target Background

The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Synonyms:SAE1; AOS1; SUA1; UBLE1A; SUMO-activating enzyme subunit 1; Ubiquitin-like 1-activating enzyme E1A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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