SATB2 Rabbit Monoclonal Antibody

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Catalog Number:MABN01482
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human SATB2
Reactivity:Rat
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 83 kDa; Observed MW: 83 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:GLSS; SATB family member 2; SATB homeobox 2; SATB2; Special AT rich sequence binding protein 2

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide of human SATB2

Target Background

Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers.

Synonyms:GLSS; SATB family member 2; SATB homeobox 2; SATB2; Special AT rich sequence binding protein 2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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