Immunological Sciences

SBDS (5N11) Rabbit Monoclonal Antibody

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Catalog Number:MABN17619
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human SBDS
Reactivity:Human,Mouse,Rat
Applications:WB 1:2000-1:20000
Molecular Weight:29kDa
Purification:Affinity purification
Form:Liquid
Synonyms:CGI 97; sbds; SDS; SWDS;

Applications

WB 1:2000-1:20000

Immunogen

A synthetic peptide of human SBDS

Target Background

Required for the assembly of mature ribosomes and ribosome biogenesis. Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

Synonyms:CGI 97; sbds; SDS; SWDS;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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