SCML2 Rabbit Polyclonal Antibody

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Catalog Number:ABN17651
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from the Internal region of human SCML2.
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000
Molecular Weight:77kDa
Purification:Affinity purification
Form:Liquid
Synonyms:SCML2; Sex comb on midleg-like protein 2

Applications

WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000

Immunogen

Synthesized peptide derived from the Internal region of human SCML2.

Target Background

This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes which are involved in transcriptional repression. The encoded protein binds histone peptides that are monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development. [provided by RefSeq, Jun 2010],function:Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the SCM family.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 MBT repeats.,tissue specificity:Highly expressed in placenta, thymus and testis. Detected at lower levels in brain, liver, skeletal muscle, pancreas and ovary.,

Synonyms:SCML2; Sex comb on midleg-like protein 2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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