Immunological Sciences

SCRIBBLE Rabbit Monoclonal Antibody

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Catalog Number:MABN86716
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human SCRIBBLE
Reactivity:Human
Applications:WB 1:1000-1:5000,FC 1:100-1:500
Molecular Weight:Calculated MW:175 kDa; Observed MW:240 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CRIB1; SCRB1; SCRIB1; Vartul

Applications

WB 1:1000-1:5000,FC 1:100-1:500

Immunogen

A synthetic peptide of human SCRIBBLE

Target Background

This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Synonyms:CRIB1; SCRB1; SCRIB1; Vartul

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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