Immunological Sciences

SEC61B Rabbit Polyclonal Antibody

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Catalog Number:ABN17695
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from human SEC61B AA range: 30-110
Reactivity:Human,Mouse,Rat
Applications:IHC 1:50-1:200,ELISA 1:5000-1:20000
Purification:Affinity purification
Form:Liquid
Synonyms:Protein transport protein Sec61 subunit beta

Applications

IHC 1:50-1:200,ELISA 1:5000-1:20000

Immunogen

Synthesized peptide derived from human SEC61B AA range: 30-110

Target Background

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008],function:Necessary for protein translocation in the endoplasmic reticulum.,similarity:Belongs to the SEC61-beta family.,subunit:Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma. Part of a complex composed of SEC61, SEC62 and SEC63. Interacts with SEC62.,

Synonyms:Protein transport protein Sec61 subunit beta

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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